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Review

“Hughes has crafted an engaging historical account of Genentech from its beginnings as a small laboratory at the University of California, San Francisco to the 2009 merger with Roche for 47 billion dollars. . . . [Her] account will appeal to a broad audience and is a must read for scholars interested in the history of biotechnology. Highly recommended.” (J. A. Hewlett Choice)“[A]n important addition to the history of biotech.” (Phillip A. Sharp, Massachusetts Institute of Technology Nature Medicine)“Over the past 20 years Sally Smith Hughes has done a great service to science studies by conducting in-depth oral-history interviews with prominent scientists, venture capitalists, corporate leaders, and attorneys in the history and business of early biotechnology. She drew on her unprecedented access to corporate records and a large number of actors and their oral histories to write Genentech, the first comprehensive account of the creation and early development of the Genentech Corporation.” (Doogab Yi Chemical Heritage Magazine)“The author skillfully reveals the practical, day-to-day, hands-on roles played by venture capitalists focused on fiscal gain and scientists focused on scientific breakthroughs. . . . [A] fascinating read.” (Valerie McGurk Nursing Standard)“[A]n eminently readable (and, for classes, eminently assignable) story . . . . Smith Hughes is one of the foremost oral historians of science today, and Genentech is filled with illuminating interview snippets woven artfully into a narrative that both engages and (somewhat surreptitiously) analyzes. . . . [F]or a case study that lays out in lively detail the ambiguities and exuberances of high-tech entrepreneurship, Smith Hughes’s Genentech surely ranks among the very best.” (Cyrus C. M. Mody, Rice University Bulletin of the History of Medicine)“[A] fascinating book, vividly recount[ing] the blood, sweat, and tears of the early days of ‘genetic engineers’ working at the bench, designing new biomolecules, and capitalizing their promises on Wall Street.” (Social History of Medicine)“Genentech: The Beginnings of Biotech paints a wonderfully detailed picture of an important beginning in the history of biotechnology.” (Nathan Crowe, Arizona State University Journal of the History of Biology)“Hughes’s Genentech makes an invaluable international contribution to understanding how a period just short of a decade redefined ‘business as usual’ for biologists.” (Lisa Onaga, Nanyang Technological University Technology and Culture)"Sally Smith Hughes skillfully describes the improbable creation, difficult adolescence, immense prosperity, and eventual foundering of Genentech, the first biotech behemoth. It’s a great tale, with a cast of fabulous characters and surprising episodes, ranging from Palo Alto to Wall Street. This is an outstanding book that should appeal to Nobel laureates as well as hedge-fund barons and ordinary citizens.” (Daniel S. Greenberg, author of Science for Sale and Tech Transfer)“Drawing extensively on oral histories, Hughes reveals the day-to-day hands-on roles of both the venture capitalists and the scientists, their eyes fixed at once on scientific triumphs and corporate riches, who brought Genentech to life. Hughes vividly recounts the tough-minded deals, buccaneering strategies, laboratory struggles, and relentless patent arrangements that not only made for Genentech’s success but that pioneered the new biotechnology industry’s operational model.” (Daniel Kevles, Yale University)

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About the Author

Sally Smith Hughes is a historian of science at the Bancroft Library at the University of California, Berkeley. She is the author of The Virus: A History of the Concept and the creator of an extensive collection of in-depth oral histories on bioscience, biomedicine, and biotechnology.

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Product details

Series: Synthesis

Paperback: 230 pages

Publisher: University of Chicago Press; Reprint edition (April 8, 2013)

Language: English

ISBN-10: 9780226045511

ISBN-13: 978-0226045511

ASIN: 022604551X

Product Dimensions:

6 x 0.6 x 9 inches

Shipping Weight: 14.4 ounces (View shipping rates and policies)

Average Customer Review:

4.7 out of 5 stars

24 customer reviews

Amazon Best Sellers Rank:

#262,463 in Books (See Top 100 in Books)

Vivid account of Genentech's founding and the early travails of the biotech industry.Things that would not immediately spring to mind today, like the deep suspicion or outright hostility of academic scientists to scientists who had an interest in business, or the paranoia surrounding the early days of genetic engineering, even in the scientific community.Somewhat uncritical acceptance of a "testosterone-charged atmosphere" as a key component of their success. Anybody who's worked with accomplished women scientists knows drive and ambition do not depend on one hormone!

My reading of Genentech follows my reading Science lessons abotu Amgen and this is a review I published elsewhere (my blog) os apologies for any inconsistency...I have to admit I had never heard of the Bancroft Library’s website (http://bancroft.berkeley.edu/ROHO/pro...) for the Program in Bioscience and Biotechnology Studies, “which centerpiece is a continually expanding oral history collection on bioscience and biotechnology [with ] in-depth, fully searchable interviews with basic biological scientists from numerous disciplines; with scientists, executives, attorneys, and others from the biotechnology industry.”The invention of new research and business practices over a very short periodSwanson was captivated: “This idea [of genetic engineering] is absolutely fantastic; it is revolutionary; it will change the world; it’s the most important thing I have ever heard.” [… But Swanson was nearly alone.] “Cetus was not alone in its hesitation regarding the industrial application of recombinant DNA technology. Pharmaceutical and chemical corporations, conservative institutions at heart, also had reservations.” [Page 32] “Whatever practical applications I could see for recombinant DNA… were five to ten years away, and, therefore, there was no rush to get started, from a scientific point of view.” [Page 32] “I always maintain” Boyer reminisced, “that the best attribute we had was our naïveté… I think if we had known about all the problems we were going to encounter, we would have thought twice about starting… Naïveté was the extra added ingredient in biotechnology.” [Page 36]The book shows the importance of scientific collaborations. Not just Boyer at UCSF but for example with a hospital in Los Angeles. A license was signed with City of Hope Hospital with a 2% royalty on sales on products based on the licensed technology. “[…] negotiated an agreement between Genentech and City of Hope that gave Genentech exclusive ownership of any and all patents based on the work and paid the medical center a 2 percent royalty on sales of products arising from the research.” [Page 57]Even if in 2000, City of Hope had received $285M in royalties, it was not happy with the outcome. After many trials, the California Supreme Court in 2008 awarded another $300M to City of Hope. So the book shows that these collaborations gave also much legal litigation. [Page 58]In a few years, Genentech could synthesize somatostatin, insulin, human growth hormone and interferon. It is fascinating to read how intense, uncertain, stressful these years were for Swanson, Perkins, Boyer and the small group of Genentech employees and academic partners (Goeddel, Kleid, Heyneker, Seeburg, Riggs, Itakura, Crea), in part because of the emerging competition from other start-ups (Biogen, Chiron) and academic labs (Harvard, UCSF).“On August 25, 1978 – four days after Goeddel’s insulin chain-joining feat – the two parties signed a multimillion-dollar, twenty-year research and development agreement. For an upfront licensing fee of $500,000, Lilly got what it wanted: exclusive worldwide rights to manufacture and market human insulin using Genentech’s technology. Genentech was to receive 6 percent royalties and City of Hope 2 percent royalties on product sales.” [Page 94] They managed to negotiate a contractual condition limiting Lilly’s use of Genentech’s engineered bacteria to the manufacture of recombinant insulin alone. The technology would remain Genentech’s property, or so they expected. As it turned out, the contract, and that clause in particular, became a basis for a prolonged litigation. In 1990, the courts awarded Genentech over $150 million in a decision determining that Lilly had violated the 1978 contract by using a component of Genentech’s insulin technology in making its own human growth hormone product. [Page 95] Perkins believed that the 8 percent royalty rate was unusually high, at a time when royalties on pharmaceutical products were along the lines of 3 or 4 percent. “It was kind of exorbitant royalty, but we agreed anyway – Lilly was anxious to be first (with human insulin)” […]The big company – small company template that Genentech and Lilly promulgated in molecular biology would become a prominent organizational form in a coming biotechnology industry. [Page 97]The invention of a new cultureYoung as Swanson was, he kept everyone focused on product-oriented research. He continued to have scant tolerance for spending time, effort, and money on research not tied directly to producing marketable products. “We were interested in making something usable that you could turn into a drug, inject in humans, take to clinical trials.” A few year before his premature death, Swanson remarked, “I think one of the things I did best in those days was to keep us very focused on making a product.“ His goal-directed management style differed markedly from that of Genentech’s close competitors. [Page 129]But at the same time Boyer would guarantee a high quality research level by encouraging employees to write the best possible scientific articles. This guaranteed the reputation of Genentech in the academic world.A culture was taking shape at Genentech that had no exact counterpart in industry or academia. The high-tech firms in Silicon Valley and along Route 128 in Massachusetts shared its emphasis on innovation, fast-moving research, and intellectual property creation and protection. But the electronics and computer industries, and every other industrial sector for that matter, lacked the close, significant, and sustained ties with university research that Genentech drew upon from the start and that continue to define the biotechnology industry of today. Virtually every element in the company’s research endeavor – from its scientists to its intellectual and technological foundations – had originated in decade upon decade of accumulated basic-science knowledge generated in academic labs. […] At Boyer’s insistence, the scientists were encouraged to publish and engage in the wide community of science. [Page 131]But academic values had to accommodate corporate realities: at Swanson’s insistence, research was to lead to strong patents, marketable products, and profit. Genentech’s culture was in short a hybrid of academic values brought in line with commercial objectives and practices. [Page 132]Swanson was the supportive but insistent slave driver, urging on employees beyond their perceived limits: “Bob wanted everything. He would say, If you don’t have more things on your plate than you can accomplish, then you’re not trying hard enough. He wanted you to have a large enough list that you couldn’t possibly get everything done, and yet he wanted you to try.” […] Fledging start-ups pitted against pharmaceutical giants could compete mainly by being more innovative, aggressive, and fleet of foot. Early Genentech had those attributes in spades. Swanson expected – demanded – a lot of everyone. His attitude was as Roberto Crea recalled: “Go get it; be there first; we have to beat everybody else… We were small, undercapitalized, and relatively unknown to the world. We had to perform better than anybody else to gain legitimacy in the new industry. Once we did, we wanted to maintain leadership.” […] As Perkins said “Bob would never be accused of lacking a sense of urgency. “ […] Even Ullrich, despite European discomfort with raucous American behavior, admitted to being seduced by Genentech’s unswervingly committed, can-do culture. [Page 133]New exit strategiesInitially Kleiner thought Genentech would be acquired by a major pharma company. It was just a question of when. He approached Johnson and Johnson and “floated the idea of a purchase price of $80 million. The offer fell flat. Fred Middleton [Genentech’s VP of finance], present at the negotiations, speculated that J&J didn’t have “a clue about what to do with this [recombinant DNA] technology – certainly didn’t know what it was worth. They couldn’t fit it in a Band-Aid mold”. J&J executives were unsure how to value Genentech, there being no standard for comparison or history of earnings.” [Page 140]Perkins and Swanson made one more attempt to sell Genentech. Late in 1979, Perkins, Swanson, Kiley and Middleton boarded a plane for Indianapolis to meet with Eli Lilly’s CEO and others in top management. Perkins suggested a selling price of $100 million. Middleton’s view is that Lilly was hamstrung by a conservative “not invented here” mentality, an opinion supported by the drug firm’s reputation for relying primarily on internal research and only reluctantly on outside contracts. The company’s technology was too novel, too experimental, too unconventional for a conservative pharmaceutical industry to adopt whole-heartedly. [Page 141]When Genentech successfully developed interferon, a new opportunity happened. Interferon had been discovered in 1957 and thought to prevent virus infection. In November 1978, Swanson signed a confidential letter of intent with Hoffmann – La Roche and a formal agreement in January 1980. They were also lucky: “Heyneker and a colleague attended a scientific meeting in which the speaker – to everyone’s astonishment given the field’s intense competitiveness – projected a slide of a partial sequence of fibroblast interferon. They telephoned the information to Goeddel, who instantly relay the sequence order to Crea. […] Crea started to construct the required probes. […] Goeddel constructed a “library” of thousands upon thousands of bacterial cells, seeking ones with interferon gene. Using the partial sequence Pestka retrieved, Goeddel cloned full-length DNA sequences for both fibroblast and leukocyte interferon. […] In June 1980, after filing patent protection, Genentech announced the production in collaboration with Roche.” [Page 145] Genentech could consider going public and after another fight between Perkins and Swanson, Genentech decided to do so. Perkins had seen that the year 1980 was perfect for financing biotech companies through a public offering but Swanson saw the challenges this would mean for a young company with nearly no revenue or product.New role modelsThe 1980-81 period would see the creation of a fleet of entrepreneurial biology-based companies – Amgen, Chiron, Calgene, Molecular Genetics, Integrated Genetics, and firms of a lesser note – all inspired by Genentech’s example of a new organizational model for biological and pharmaceutical research. Before the IPO window closed in 1983, eleven biotech companies in addition to Genentech and Cetus, had gone public*. […] But not only institutions were transformed. Genentech’s IPO transformed Herb Boyer, the small-town guy of blue-collar origins, into molecular biology’s first industrial multimillionaire. For admiring scientists laboring at meager academic salaries in relative obscurity, he became a conspicuous inspiration for their own research might be reoriented and their reputation enhanced. If unassuming Herb – just a guy from Pittsburgh, as a colleague observed – could found a successful company with all the rewards and renown that entailed, why couldn’t they? [Page 161]*: According to one source, the companies staging IPO were Genetic Systems, Ribi Immunochem, Genome Therapeutics, Centocor, Bio-Technology General, California Biotechnology, Immunex, Amgen, Biogen, Chiron, and Immunomedics. (Robbins-Roth, From Alchemy To Ipo: The Business Of Biotechnology)

The title pretty well explains the subject of Genentech. Hughes does not spare scientific detail, but she writes about it deftly, blending the science into the narrative. Readers with even the most basic understanding of genetics will hardly notice that they have gotten a short lesson on recombinant technology along with a great story.

The story of Genentech is pretty astounding. I have followed this company for a number of years. This company warranted the book, duly named. It was somewhat sensationalized, but easy to read and understand, even for someone with no ties or connection to the industry. I literally read it on a flight from la to san francisco including the time spent in the airport before takeoff. It was a great flight.

The book covers the beginnings of Genentech and serves as a useful case study for the biotech industry - a great resource for all the biotech startups today.

A well-paced and thoughtful history that successfully balances the personalities, drama, economics and science of the topic.

It is a very well written, interesting to read and learn as was creating one of the leading biotech companies book. From here begins another story. I recommend to read and use in teaching and research

Excellent

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Audible Audiobook

Listening Length: 12 hours and 8 minutes

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Publisher: SmartPass

Audible.com Release Date: October 28, 2009

Language: English, English

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PDF Download The Algorithmic Leader: How to Be Smart When Machines Are Smarter Than You, by Mike Walsh

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Review

“Provocative, powerful, and full of actionable wisdom. The Algorithmic Leader is a tour de force of ideas and insights from global pioneers who are challenging the status quo and reinventing organizations. Mike Walsh has produced a must-read for every leader and entrepreneur in this digital age.”―Daniel Hulme, Founder & CEO of Satalia"This book first made me deeply uneasy, and then deeply inspired. Like you, I wrestle with how best to thrive as our world grows increasingly complex and confusing, a world where the simple rules just don’t work anymore. Mike Walsh’s ten principles, distilled from real-life experience and deep thinking, point the way forward."―Michael Bungay Stanier, author of the Wall Street Journal bestseller The Coaching Habit“Great companies are built on culture. Mike Walsh’s prescient vision of the algorithmic company of the future is no robot army of soulless analytics dashboards, but a living, breathing organism―a community of humans who respond to motivation beyond compensation; purpose and impact; decision-making and autonomy; location and collaboration. A worthy read.”―Brian Halligan, Founder & CEO of Hubspot“Mike Walsh provides an interesting and informative look at our future, which will be defined by algorithms and artificial intelligence. The underlying technologies may seem complex, but the message for business leaders is simple: use the new tools to enhance your skills―or become roadkill.”―Vivek Wadhwa, Distinguished Fellow, Harvard Law School, Labor and Worklife Program and author of The Driver in the Driverless Car“Mike Walsh’s years of talking to the world’s technology leaders have given him unusually deep insight into the ways in which technology will change our world. Now he has written a powerful book that enables the rest of us to gain that insight. This book will change the way you think. Full of rich examples and great quotes, it is like a hyperspeed trip into the future that will give you a whole new perspective on your industry and career.”―Melissa Schilling, author of Quirky and Strategic Management of Technological Innovation“Mike Walsh’s The Algorithmic Leader is an intelligent and timely look at leadership in the digital age. If the twentieth century was governed by leaders of people, the twenty-first will be governed by leaders who understand the relationship between people and the technologies that define the modern workplace. Walsh exposes not just opportunities, but also potential pitfalls, ultimately leaving today’s leaders smarter and better prepared for the coming rise of algorithms and big data.”―Adam Alter, author of the New York Times bestseller Irresistible and Drunk Tank Pink“I have read many thousands of pages about the impact of algorithms and automation on our lives, and Mike Walsh’s The Algorithmic Leader stands out from the crowd. It is honest in its complexity, practical in its lessons, and profound in its analysis of the future of work. It’s a must-read for anyone contemplating how smart humans can collaborate with smart machines.”―David Epstein, author of the New York Times bestseller The Sports Gene and Range“The Algorithmic Leader is brilliant and scary. The scale of change that AI is bringing into our lives can be bewildering. In this timely book, Mike Walsh provides (often counterintuitive) ideas and fascinating insights into what the coming decades will bring. 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He paints a future for leadership that has a lot more in common with the art of gardening than the art of war. Great gardeners start with a great vision and then focus on creating an ecosystem that understands, nourishes, and tends, allowing all to become their strongest, no matter what uncertainties they face, until they brilliantly fruit and blossom. Walsh’s principles tell us how it should be done, but then he passionately shows that it is not the ‘how’ that matters but the ‘why’: to make our world a better place for all of humanity to flourish.”―Ali Parsa, founder & CEO of Babylon Health

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About the Author

Mike Walsh is the CEO of Tomorrow, a global consultancy on designing companies for the twenty-first century. He advises leaders on how to thrive in the current era of disruptive technological change. A true global nomad, Mike travels over 300 days a year worldwide, researching trends, collecting case studies, and presenting on the future of business. Mike's clients include many of the global Fortune 500, and as a sought-after keynote speaker he regularly shares the stage with world leaders and business icons alike. Mike previously founded Jupiter Research in Australia, and has also held senior strategy roles at News Corporation in the Asia Pacific region. Mike's other books include Futuretainment and The Dictionary of Dangerous Ideas. Each week he interviews provocative thinkers, innovators, and troublemakers on his podcast, Between Worlds.

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Product details

Hardcover: 256 pages

Publisher: Page Two (March 12, 2019)

Language: English

ISBN-10: 1989025331

ISBN-13: 978-1989025338

Product Dimensions:

6.5 x 1 x 9.2 inches

Shipping Weight: 1.2 pounds (View shipping rates and policies)

Average Customer Review:

5.0 out of 5 stars

4 customer reviews

Amazon Best Sellers Rank:

#27,321 in Books (See Top 100 in Books)

If technology and artificial intelligence seems complicated or confusing to you, then this is a must-read book from Mike Walsh’s futuristic vision. It is inspiring and groundbreaking for our present and future digital world whether you are an entrepreneur, business owner or just at the beginning of your career.Amazing story telling from the author and his interviews with some of the greatest leaders in their sectors. Definitely recommend this eye-opening book.

The authors insight on the future and how these new leadership principles apply, is literally uncanny. I think this book will ultimately become a “how to fly” manual for the modern leader. Great book!

This book was a gift from a friend. A great and thought provoking read as with many of the authors books and articles. Would highly recommend.

Great book! It is an invitation to see how the future is being created globally. AI will continue to disrupt business, but also to dig a social divide that only good education can close.

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Free Download Majestic Rose Nouveau Bible Tabs, by Ellie Claire

Free Download Majestic Rose Nouveau Bible Tabs, by Ellie Claire

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Majestic Rose Nouveau Bible Tabs, by Ellie Claire

Free Download Majestic Rose Nouveau Bible Tabs, by Ellie Claire

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After getting the data of the Majestic Rose Nouveau Bible Tabs, By Ellie Claire, you have to know how to handle your time to read. Of course, lots of people will certainly have different methods to organize the time. You could use it in your leisure in the house, at the workplace, or at the evening prior to resting. The book file can be also kept as one of the presented analysis product

Product details

Misc. Supplies

Publisher: Ellie Claire Gifts; Nov edition (July 1, 2008)

Language: English

ISBN-10: 1934770981

ISBN-13: 978-1934770986

Product Dimensions:

3.2 x 0.1 x 6.5 inches

Shipping Weight: 2.4 ounces (View shipping rates and policies)

Average Customer Review:

4.5 out of 5 stars

581 customer reviews

Amazon Best Sellers Rank:

#989 in Books (See Top 100 in Books)

Pretty and makes bible look lovely 💘

I've been using my Bible more recently and had originally purchased Majestic Bible Tabs Lavender. I had great success with those and wanted to get more tabs to put in the two other Bibles I own. I ended up purchasing these rose nouveau tabs, along with Majestic Traditional Gold-Edged Bible Tabs.These tabs are perfect for bigger Bibles and the one I put these in measures about 9 1/2 inches tall. This package of tabs contains 72 foil-edged tabs and the books of the Bible are printed on both sides. The tabs are pink with a floral design on them and the rose-color foil edges add a beautiful accent. Each tab measures about one inch wide by 1/4 inch high. There are a total of six sheets of tabs for the books in the Old and New Testaments, along with some extra tabs for Notes, Special, Concordance, Index, Old and New Testaments, Maps, and Life Verse. Please note, these tabs won't work well for Catholic Bibles since they don't contain blank tabs for the additional books in that Bible. If you have a Catholic Bible, I'd recommend purchasing Majestic Traditional Gold-Edged Bible Tabs. I have those as well for one of my Bibles and they are the same as these, just a gold color. There are detailed instructions and a guide included in this package to help you attach the tabs. These tabs are made in China.I've now successfully attached three sets of these tabs, in different colors, and here are some tips I've discovered:- I definitely wouldn't rush since these tabs are like stickers and, once they are fully stuck on the thin Bible pages, they may be difficult to fix. Before you attach both clear sticky pieces, you MAY be able to gently remove them and adjust as necessary. I've been able to do this with no problems.- When you start a new sheet of tabs, fold along the foil edges BEFORE removing the tabs and attaching them. This will make it easier to fold them over when you attach them.- I've found it's easiest to pull the tabs off the sheet by peeling the colored part off first instead of the clear parts. This will help prevent the tabs from ripping.- Use the guide to help you attach the tabs and, if you ever forget which tab number you are on (e.g. 4,5,6...), just look back at your previous tab and count down to find which number you will use next.- The tabs will always be attached to the pages on the right side, regardless of where the beginning of the book starts. Sometimes my tabs are attached to the title page and sometimes they are on the page with the first couple of chapters.- If your Bible contains words that go to the edges of the pages, don't worry about these tabs covering them up. The only parts that are actually attached to the pages are the clear sticky tabs so you can still easily read your Bible.- After you've attached a tab and it looks straight enough, carefully make sure there is only one page attached and fold over the tab to the other side of the page. Once the tabs are in place, I always press them firmly down.- When I'm opening my Bible using these tabs, I don't pull on the tabs themselves. Instead, I find the book I want, slide my finger in, and open my Bible that way.I've now applied three sets of these tabs and they have all worked well for me! I love the colors and design choices available since everyone has different personalities. I feel these are very affordable and easy to apply, once you get the hang of it. It generally takes me about an hour to apply all of my tabs and I am pleased with the results. These tabs make reading my Bible easier, more efficient, and fun! If you are looking for tabs for your Bible, these are a great option. They won't work for Catholic Bibles but there are some options for those too. I highly recommend these tabs!

Easy to use. Came with instructions and a guide line. I love the quality and choice of colors. Thank you!

Haven't had them in my bible for a month and the shiny pink foil is already scraping off. Can't imagine how they will look after a few more months.

Very pretty... but the pink foil edge scrapes off way too easily. Someone else wrote a review saying this, but I assumed that they were probably taking it many places and stuffing it in a bag or something. I was wrong. I took my brand new bible with these brand new tabs to church for the first time today and the foil has already rubbed off a little on some of the tabs. This kills me because I am a perfectionist and like to keep my things looking nice and new for as long as possible. I was very careful with my bible and it still happened on DAY ONE!They look so nice when they are new though. If I had known, I think I would've found a way to laminate the edges.

These tabs are gorgeous! I love everything about them. Please note that they are not compatible with a Catholic Bible. This company does have other tabs that include the Catholic books. I called customer service and was given a refund right away so I could buy new tabs that will work. I highly recommend these tabs if you do not have a Catholic Bible.

These seem nice quality tabs. The color goes perfectly with my NIV Journal the Word women's Bible. The tabs were easy to attach using the guide. Just needs a lite touch till you are sure it's aligned to your satisfaction. I was able to gently unpeel parts if it contacted with the thin Bible pages before I was ready. Had no tearing. But I will make very clear, these are NOT to be adhered then moved. These are meant to be placed once then left on. But if you move quickly and ever-so-gently, if it attaches in a unwanted spot, you should be able to move. Very pleased and would repurchase. Ps. They have a coating on them that should protect them from ripping with normal, gentle use.

I wanted to add tabs to my new study Bible, and when I saw these, I had to get them! Beautiful pink color, shiny foil accents - what's not to love? They were pretty simple to put on, especially when I used a couple of small strips of washi tape to temporarily hold the guide on the page to keep it in place while sticking on the tab. They look great, and with reasonable care not to manhandle the pages, shouldn't rip. Definitely recommended.

I bought these to match my Bible. Pink is my favorite color and these are so pretty period very easy to put on and they are secure. The only thing I did not like was the fact that for the book of Deuteronomy it is not spelled out completely. It says Deuteron. Other than that these are wonderful and pretty and they match my Bible so well.

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Free Ebook

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File Size: 63717 KB

Print Length: 215 pages

Simultaneous Device Usage: Up to 5 simultaneous devices, per publisher limits

Publisher: New Riders; 1 edition (October 9, 2012)

Publication Date: October 9, 2012

Sold by: Amazon Digital Services LLC

Language: English

ASIN: B009ONZ0MM

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#167,576 Paid in Kindle Store (See Top 100 Paid in Kindle Store)

Jakob Nielsen has a long-established reputation for understanding how we use the internet, and admonishes us to design around the user's natural inclinations, not try to reengineer the user or guide her mouse-clicks. In an ever increasingly complex world, he has made a career teaching us to keep it simple.He co-founded the Nielsen Norman group (NN/g) to preach and teach usability, and its staff are all rocket-scientist-caliber researchers who teach from facts and figures, solid research all.In "Mobile Usability", he teams up with NN/g researcher Raluca Budiu to produce a wonderfully narrated, extensively illustrated and entertaining read, showing us by numerous examples why we must simplify our website designs for the mobile device. Screen real estate is the prime constraint, and most websites which work on the 20" desktop cannot function on the hand-held device, unless we strip away the unnecessary 'chrome', assure that our page links are easily 'discoverable', and each precious user click offers high 'affordance' - you get the content you want and expect when you click a link.These simple guidelines are easily adopted by even novice web designers, and should be read by anyone designing mobile websites. A seventh grader can read and understand this book, and that's my definition for good writing.The examples range from ordering a Pizza to browsing the news; the sites featured all are targets for improvement in usability. Martha Stewart's site emphasizes cutesy over discoverability - good luck figuring out what is a hyperlink. Pizza Hut will starve you by the time you order dinner for carry-out on your cell phone (BTW this is still true; last night I tried to order a Pizza from my Android but got so frustrated I finally called the store to manually order). And so on. The examples are profoundly instructive.For those who find this book pricey, know that the NN/g staff publishes a wealth of articles on their website for free. Their writers may be mostly Harvard PHD types, but you don't have to drop major coin or enroll in post-grad courses to benefit from their knowledge.Yet, if you have the few bucks for a classic paperback you'll read over and again, this one sells for fifteen bucks for the Kindle, and new for half-retail. I actually bought mine for full list at the bookstore as an impulse buy, and it was worth every penny with the next site I designed.Furthermore, I just saw that Nielsen's "Designing Web Usability" is selling used for one penny and up (plus shipping, for sure), and it is still the BIBLE for web authors. So if you endeavor to design websites that just plain work, order that one too...Read, learn, write simply, educate others.Bob Reedtechwriter1@comcast.net

Whichever page you open this book at, you'll find common sense advice that you'd think anyone could come up with on their own. Unfortunately, reality has taught us that developers perform quite poorly at understanding how users want to interact with their applications (I'm a developer myself, and I know how true that is from first hand experience).The book is quite good at explaining why some decisions (actual decisions, made by real people in real applications) are bad, and why others are good -- and when you see other developers' apps analyzed like that you can't help but agree with the authors. Of course, you might have a different perspective on things if you are one of the developers who performed poorly, but this is what this book is all about: helping us avoid mistakes we know we're inclined to make in the first place. And that's the whole point of reading it.

This is probably the most scientific approach to UI/UX you'll find. There are literally hundreds of valuable tips herer for improving UI/UX, and each is thoroughly justified and validated with actual scientific measurements.

Jakob Nielsen is famous among the HCI community for his heuristics, which are as valid today as they were back in 1994 when they were created. With this publication, he has shown that he is also in tune with the more recent mobile world. A good read for UX practitioners in the mobile space.

Tough to really learn much from a book discussing new tech during its infancy. It is thought provoking, interesting and a quick read.

I think that it could be shorter. The content was not that huge...I think that it is lacking a mobile usability testing chapter too.

I would recommend this book to all UX professionals and mobile apps designers as it presents many valuable guidelines and hints for app development and testing. However, I was a little bit disappointed by the number of remarks that might be obvious even for a fresh user of a smarthopne or a tablet.

Not a bad book, lots of research to support theories in this book. I personally felt some of the conclusions drawn from some of the research weren't accurate based on how they were presenting it or that they could have been concluded a different way from the same data, but overall great points to consider. The book seemed a bit dated and probably is.

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Free Ebook Software Law and Its Applications (Aspen Casebook)

Free Ebook Software Law and Its Applications (Aspen Casebook)

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Software Law and Its Applications (Aspen Casebook)

Free Ebook Software Law and Its Applications (Aspen Casebook)

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Product details

Series: Aspen Casebook

Hardcover: 600 pages

Publisher: Wolters Kluwer Law & Business (January 7, 2014)

Language: English

ISBN-10: 1454835990

ISBN-13: 978-1454835998

Product Dimensions:

8 x 1.2 x 10.5 inches

Shipping Weight: 2.5 pounds (View shipping rates and policies)

Average Customer Review:

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Amazon Best Sellers Rank:

#660,162 in Books (See Top 100 in Books)

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Ebook Download The Field Guide to Understanding 'Human Error'

Ebook Download The Field Guide to Understanding 'Human Error'

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The Field Guide to Understanding 'Human Error'

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Audible Audiobook

Listening Length: 3 hours and 58 minutes

Program Type: Audiobook

Version: Unabridged

Publisher: Sidney Dekker

Audible.com Release Date: May 11, 2018

Language: English, English

ASIN: B07CY9SSF2

Amazon Best Sellers Rank:

It's definitely worth a read, but it seriously needs the assistance of a professional editor before the next revision. The message is in there, buried under layers of redundancy so thick you'd swear they had a target word count they were aiming for. I can sum it up thusly: "You can't understand why an accident occurred until you discover why the actions taken that led up to it made sense at the time. Pointing out mistakes made along the path to disaster is nowhere near as useful as figuring out why the people who made them didn't know they were mistakes".

This book is the perfect introduction to systems thinking when trying to understand accidents, improve safety, and make systems more resilient. The examples are great, and the author's perspective comes through loud and clear. He puts in clear relief the "old way" and "new way" of thinking about error, lays out his case for transitioning to the new way, and does it all clearly and concisely. Great read! I'll be buying extra copies to lend to colleagues.

I am an airline pilot and i have been greatly influenced by the work of Tony Kern. The Field Guide closed a gap on my knowledge about discipline and compliance. Five stars.

This book plus Dr. Conklin's pre accident investigations has completely altered my thinking. I've been in the safety field for 15+ years.. my thinking of human error was misaligned.. I strongly recommend this book to anyone in HSE or operations or businesses that hurt people

very helpful at understanding the language and intent of accident investigation and offers insight into the cause and effect of action taken in advance of adverse events

Quite an interesting take on accident investigation and understanding human error. The paradigm of the investigator placing themselves "inside the tunnel" to avoid hindsight bias is a powerful metaphor.Some of the chapters get to be a bit hard going - with lots of restating the basic tenet of Old View vs New View though.All in all - quite thought provoking and worth a read.

Found the book interesting and helpful. In am in Process Safety and it made me think about how I do HAZOPs and PHAs. This version is better organized than revision 2.

Looking forward to see the New View in progress. I would recommend this book to all involved in safety management and all the practitioners whom really cares about a safety culture and safe flights. We must understand that safety is in our hands and it's our responsibility to improve it as much as we can.

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